Wednesday, October 6, 2010

Did India miss a medicine Nobel?


Robert Edwards of Britain won the 2010 Nobel Prize in medicine for the development of in-vitro fertilization, a ground-breaking process that has helped many couples over the last two decades have children.
While Edwards was working towards his dream - creating the world’s first in vitro fertilized or test tube baby - a physician in India was working on the same subject but the odds were piled heavily against him.
Bengali doctor Subhash Mukhopadhyay was two months late in announcing the birth of Durga or Kanupriya Agarwal - India’s first test tube baby created by him on October 3, 1978.




While Edwards, professor emeritus at University of Cambridge, was lauded for his efforts, Mukhopadhyay was fighting a hostile state government that rubbished his findings. Ridiculed and ostracised, Mukhopadhyay was also not allowed to publicise his work in the international arena.
He was invited by the Kyoto University in 1979 to present his findings during a seminar in Japan but denied a passport by the Indian government. The depressed physician committed suicide in 1981.
Here are some facts about the man considered the father of India’s IVF research, who remained unsung during his lifetime but inspired many physicians after his death to bring his life and work to the public domain.
So who was Dr. Subhash Mukhopadhyay?
Born on January 16, 1931 in Bihar, Mukhopadhyay studied medicine at the prestigious National Medical College in Kolkata. He received his doctorate from Calcutta University in reproductive physiology in 1958. He obtained a second doctorate from Edinburgh in reproductive endocrinology.
He was noted for his work on ovarian stimulation - he used the protocol successfully on Durga’s mother even before any scientist in the world had resorted to the method.
He was also successful in his methodology of cryopreservation of a eight cell embryo.
However, the news of the birth of Durga, the world’s second test tube baby, was met with disdain and skepticism by his peers.
The only evidence of his work was a report he had prepared for the West Bengal government facing an enquiry. He was questioned by a government committee several times and his work was discredited as “bogus”.
What went against Dr. Mukhopadhyay then was the fact that no physiological or biochemical technique could distinguish between in vivo and in vitro fertilised babies.
He was transferred to the ophthalmology department of Calcutta Medical College in 1981 and prevented from completing his work on IVF.
Mukhopadhyay had no documented evidence and the credit for bringing his work to the public domain is largely given to Dr. T C Anand Kumar who was recognized officially as the first to deliver a test tube baby in 1986.
Kumar went through Mukhopadhyay’s notes and credited the doctor posthumously for his pioneering work.
Medical scientists opine that had Mukhopadhyay been allowed to publish his work and given adequate government funds and infrastructure to complete his research, he would have been recognized as the pioneer in in vitro fertilization process, hopefully paving the way for a Nobel prize in medicine such as his precursor Edwards.
The Indian Council of Medical Research in 2005 acknowledged Mukhopadhyay as the creator of India’s first test tube baby.
Filmmaker Tapan Sinha, who was deeply impressed by Mukhopadhyay’s work, based his award-winning film ‘Ek Doctor Ki Maut’ on him.

Monday, October 4, 2010

Quotables


"Great minds discuss ideas

 Average minds discuss events

 Small minds discuss individuals”                                         – Anon



“Education is the most powerful weapon which you can
 use to change the world.”
                                                                                              - Nelson Mandela


“Strength does not come from physical capacity. It comes
 from an indomitable will.”
                                                                                                       - M.K.Gandhi


“Failure is simply the opportunity to begin again, this time
 more intelligently.”
                                                                                                       - Henry Ford

“Nothing is permanent in this wicked world - not even our
  troubles.”
                                                                                               - Charlie Chaplin

“It is possible to fly without motors, but not without knowledge
 and skill.”
                                                                                                  - Wilbur Wright

“I never did a day's work in my life. It was all fun.”
                                                                                               -  Thomas Edison


“Take up one idea. Make that one idea your life - think of
it, dream of it,live on idea. Let the brain, muscles,
nerves,every part of your body, be full of that idea, and
just leave every other idea alone. This is the way to success.”
                                                                                     -  Swami Vivekananda




















Thursday, September 16, 2010

Social Entrepreneurship

Social entrepreneurs are individuals with innovative solutions to society’s most pressing social problems. They are ambitious and persistent, tackling major social issues and offering new ideas for wide-scale change.
Rather than leaving societal needs to the government or business sectors, social entrepreneurs find what is not working and solve the problem by changing the system, spreading the solution, and persuading entire societies to take new leaps.
Social entrepreneurs often seem to be possessed by their ideas, committing their lives to changing the direction of their field. They are both visionaries and ultimate realists, concerned with the practical implementation of their vision above all else.
Each social entrepreneur presents ideas that are user-friendly, understandable, ethical, and engage widespread support in order to maximize the number of local people that will stand up, seize their idea, and implement with it. In other words, every leading social entrepreneur is a mass recruiter of local change makers—a role model proving that citizens who channel their passion into action can do almost anything.
Over the past two decades, the citizen sector has discovered what the business sector learned long ago: There is nothing as powerful as a new idea in the hands of a first-class entrepreneur.
The differences between “entrepreneurship” and “social entrepreneurship”
A social entrepreneur is any person, in any sector, who uses earned income strategies to
pursue a social objective, and a social entrepreneur differs from a traditional entrepreneur in two
important ways:
• Traditional entrepreneurs frequently act in a socially responsible manner: They donate money to nonprofits; they refuse to engage in certain types of businesses; they use environmentally safe materials and practices; they treat their employees with dignity and respect. All of this is admirable, but their efforts are only indirectly attached to social problems. Social entrepreneurs are different because their earned income strategies are tied directly to their mission: They either employ people who are developmentally disabled, chronically mentally ill, physically challenged, poverty stricken or otherwise disadvantaged; or they sell mission-driven products and services that have a direct impact on a specific social problem (e.g., working with potential dropouts to keep them in school, manufacturing assistive devices for people with physical disabilities, providing home care services that help elderly people stay out of nursing homes, developing and selling curricula).
• Secondly, traditional entrepreneurs are ultimately measured by financial results: The success or failure of their companies is determined by their ability to generate profits for their owners. On the other hand, social entrepreneurs are driven by a double bottom line, a virtual blend of financial and social returns. Profitability is still a goal, but it is not the only goal, and profits are re-invested in the mission rather than being distributed to shareholders.

Historical Examples of Leading Social Entrepreneurs:

  • Susan B. Anthony (U.S.): Fought for Women's Rights in the United States, including the right to control property and helped spearhead adoption of the 19th amendment.
  • Vinoba Bhave (India): Founder and leader of the Land Gift Movement, he caused the redistribution of more than 7,000,000 acres of land to aid India's untouchables and landless.
  • Dr. Maria Montessori (Italy): Developed the Montessori approach to early childhood education.
  • Florence Nightingale (U.K.): Founder of modern nursing, she established the first school for nurses and fought to improve hospital conditions.
  • Margaret Sanger (U.S.): Founder of the Planned Parenthood Federation of America, she led the movement for family planning efforts around the world.
  • John Muir (U.S.): Naturalist and conservationist, he established the National Park System and helped found The Sierra Club.
  • Jean Monnet (France): Responsible for the reconstruction of the French economy following World War II, including the establishment of the European Coal and Steel Community (ECSC). The ECSC and the European Common Market were direct precursors of the European Union.

Thursday, September 9, 2010

The 7 habits of highly innovative people


Habit 1: Be Passionate. Finding your passion is not only the key to happiness, but also the key to business success. As Steve Jobsonce said, “Your time is limited, so don’t waste it living someone else’s life. The only way to do great work is to love what you do. If you haven’t found it yet, keep looking. Don’t settle.” (Be Proactive)
Habit 2: Do Something. You don’t always know where it’s going to lead, but it’s always better to do something than to suffer analysis paralysis. Legendary oil-man and entrepreneur T. Boone Pickenshas a way of quickly sizing up a situation, coming up with a plan, and acting. There’s no sitting around or endless analysis and debate. It seems to have worked for him. (Begin with the End in Mind)
Habit 3: Put First Things First, Second, and Third. Covey says prioritize, but I’ll take it one step further. Whoever said, “don’t sweat the small stuff,” was right, and I’ll add, “don’t do or even think about the small stuff.” Every successful innovative person I know jumps on hot opportunities and critical issues like they’re the only things that matter on god’s green Earth. (Put First Things First)
Habit 4: Think Win. Former New York Yankees owner George Steinbrenner may have been a world-class a-hole, but he was a remarkably rich and successful world-class a-hole who let nothing stand in the way of the only thing that ever really mattered to him, winning. Bill GatesLarry Ellison - show me a successful entrepreneur and I’ll show you someone who puts winning first.(Think Win/Win)
Habit 5: Seek First to Understand, then to Innovate. The key to innovation is to first understand a big hairy problem that, to date, nobody’s been able to solve. Once you’ve got that, then, and only then, does it even begin to make sense to do something about it. Otherwise you’ll just end up with a great product nobody needs.(Seek First to Understand, then to be Understood)
Habit 6: Energize. With rare exception, successful innovators are high-energy people with a unique ability to stimulate and motivate others. That’s called leadership. Without it, you can have the most effective habits or the best ideas in the world, but nobody will ever know it, because nobody will care and nothing will actually get done.(Synergize)
Habit 7: Question the Status Quo. Andy Grove built semiconductor powerhouse Intel on several principles, two of which were “only the paranoid survive” and “constructive confrontation.” That means never rest on your laurels, continually challenge your own assumptions, and always question the status quo. That’s how Intel became a high-tech dynasty. (Sharpening the Saw)